Advancement of next generation sequencing and high-throughput technologies has resulted in generation of multi-level of 'OMICS' data for many organisms. However, these data are often individually scattered across different repositories based on data type, making it difficult to integrate them. A hallmark of modern biology is tremendous amounts of complex omics data, which require large-scale data management, comprehensive computational analyses, and efficient integration, for better understanding of the data and hypothesis generation. For most biological organisms ranging from plants to animals to viruses and bacteria with sequenced genomes, there is an increasing need for the community to have a one-stop interactive, web-based portal to browse, access, analyze, integrate and share knowledge about genomics and molecular mechanisms, with ultimate links to phenotypes and traits.